You can see the talks on their schedule page - with each talk on the schedule attached to the abstract of the talk so you can easily pick what you are interested it.
This will be the 5th Plone Symposium East, a ritual for Plone enthusiasts all over the US and abroad. The event's focus on educational talks as well as general interest material has long made it a favorite from Plonistas The event is held in State College, Pennsylvania, May 22 and 23, 2012.
The event also offers a great slate of training classes held in the days prior to the conference.
Finally - remember that Monday, March 19th is the deadline for registering at a discounted earlybird rate. If you register by Monday, the discounted fee is $285, afterwards it will be $260. Registration is open now so make sure you register by Monday.